Small, sequence-designed oligonucleotide binders built around a chosen protein site and function.

Sequence-designed oligonucleotides
Nemdx designs small 2-prime-O-methyl oligonucleotides using nucleotide/amino-acid residue matching informed by the target protein sequence and selected binding region.

Function is part of the design brief
The process begins with what the molecule needs to do: engage a selected protein interface, support uptake into cells, or generate a measurable signal from protein abundance, state or function.

A common platform for drug and biomarker development
The same molecular-design approach can create a molecule intended to change biology and a complementary molecule or assay intended to measure that biology – a potentially useful pairing for therapeutic development.

Partner on a therapeutic target
CTA: Discuss a target