Your partner in Engineered Affinity
Our Mission:
Our Vision:
Our Offering:
Cutting-Edge Technologies:
Our revolutionary synthetic short RNA binders ensure ultra-high specificity and sensitivity in binding to targeted proteins/peptides. Our first diagnostic products run on standard instrumentation, using minimal sample volumes, saving time and resources. Our novel approaches enable unrivaled target specificity and sensitivity, outperforming conventional methods and accelerating product development.
SCIENCE
Science is witnessing a golden age of RNA research. The significance of this remarkable molecule was further highlighted when the 2024 Nobel Prize in Medicine honored the discovery of miRNA – a finding that transformed our understanding of how genes are controlled in living cells.
Think of RNA as nature’s versatile messenger. Traditional RNA molecules like miRNA and siRNA work as genetic regulators, essentially acting as “volume controls” for protein production in cells. While revolutionary, this approach has its limitations, as it relies on complex cellular machinery and indirect routes to achieve its effects.
At Nemdx, we’ve taken a bold step in a different direction. Rather than following the conventional path of genetic regulation, we’ve engineered synthetic RNA molecules that do something unprecedented: they bind directly to proteins themselves. This is like the difference between adjusting a factory’s production line (traditional RNA approaches) and creating a tool that can directly interact with the finished product (our approach).
Why does this matter?
– Faster: Direct protein interaction means more immediate effects
– More precise: Our synthetic RNA can be designed to target specific regions of proteins
– Versatile: This approach opens up entirely new possibilities for detecting and monitoring disease markers
– Practical: By bypassing complex cellular machinery, we’ve created a more streamlined approach
At Nemdx, we’re not just following nature’s lead – we’re charting new territories in RNA science. Our platform represents a fundamental shift in how we can use RNA technology, with far-reaching implications for medical diagnostics and biotechnology.
The following comparison illustrates how our innovative approach stands apart from existing RNA technologies:
Synthetic short RNA
- Synthetic construct
- Optimized engineered affinity
- Nuclease resistant
- Hairpin loop option
- 14 - 90+ nucleotide length
miRNA
- Natural regulator
- Natural affinity
- Easily degraded
- Single stranded
- 19 - 25 nucleotide length
siRNA
- Natural silencer
- Natural affinity
- Easily degraded
- Double stranded
- 21- 23 nucleotide length
Read More About
A Collective of Visionary Innovators and Tech Experts Committed to Pioneering Breakthroughs in RNA Science and Transforming the Future of Biotechnology.
Nemdx Assays:
A new standard for Researchers and Labs
- Neurodegenerative diseases
- Cancer research
- Infectious diseases
- Pharmaceutical studies
Your Partner in
engineered affinity:
- High accuracy and precision in detecting disease markers or biomolecules
- Detection of low concentrations of biomarkers with minimal false positives or false negatives
- Quick turnaround times enable researchers to monitor patient responses to therapies and make adjustments as needed
- Low sample volume requirements to allow non-invasive or less invasive testing
Uncover the Innovative Processes Driving Breakthroughs in RNA Technology, From In-Silico Design to Clinical Trials, Shaping the Future of Precision Medicine.
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NEMDX
Locations
- Headquarters: Boston, MA, USA
- R&D Lab: Discovery Park, Sandwich, UK
- Commercial Lab: Framingham, MA, USA