Science
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Nemdx pioneers a revolutionary approach to manipulating RNA beyond nature’s blueprint. Our innovation reshapes RNA-protein interactions to advance medical science and biotechnology.
SCIENCE
Science is witnessing a golden age of RNA research. The significance of this remarkable molecule was further highlighted when the 2024 Nobel Prize in Medicine honored the discovery of miRNA – a finding that transformed our understanding of how genes are controlled in living cells.
Think of RNA as nature’s versatile messenger. Traditional RNA molecules like miRNA and siRNA work as genetic regulators, essentially acting as “volume controls” for protein production in cells. While revolutionary, this approach has its limitations, as it relies on complex cellular machinery and indirect routes to achieve its effects.
At Nemdx, we’ve taken a bold step in a different direction. Rather than following the conventional path of genetic regulation, we’ve engineered synthetic RNA molecules that do something unprecedented: they bind directly to proteins themselves. This is like the difference between adjusting a factory’s production line (traditional RNA approaches) and creating a tool that can directly interact with the finished product (our approach).
Why does this matter?
– Faster: Direct protein interaction means more immediate effects
– More precise: Our synthetic RNA can be designed to target specific regions of proteins
– Versatile: This approach opens up entirely new possibilities for detecting and monitoring disease markers
– Practical: By bypassing complex cellular machinery, we’ve created a more streamlined approach
At Nemdx, we’re not just following nature’s lead – we’re charting new territories in RNA science. Our platform represents a fundamental shift in how we can use RNA technology, with far-reaching implications for medical diagnostics and biotechnology.
The following comparison illustrates how our innovative approach stands apart from existing RNA technologies:
Nemdx synthetic RNA
- Protein, DNA, RNA targets
- Direct protein binding
- Binds to any protein
- Synthetic production
- Engineered from amino-acids
miRNA / siRNA
- DNA, RNA targets
- Controls protein production
- Regulates gene expression
- Cellular machinery dependent
- Cellular factors needed
Impact
- Optimized binding to proteins
- High sensitivity/specificity
- Broad clinical applications
- Reliable reproducibility
- Streamlined development