Process
Nemdx synthetic short RNA binder: surpassing the limitations of other binding technologies
- DNA stores genetic information
- mRNA carries the genetic code transcribed from DNA
- Ribosomes act as the “gear box” for translation
- tRNA translates 3 nucleotides to 1 amino acid, facilitating the translation process
At Nemdx, we apply, to a given targeted protein, our process for optimizing RNA-protein binding:
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Characterize RNA - protein binding in silico by analyzing the physiochemical properties of interactions between amino acids and nucleotides and identify optimal binding site(s)
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Validate optimal binding in silico by maximizing amino acid - nucleotide affinity
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